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JCI - Therapeutic manipulation of peroxynitrite attenuates the development of opiate-induced antinociceptive tolerance in mice

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Morphine tolerance is attenuated in germfree mice and reversed by probiotics, implicating the role of gut microbiome

Reactive Oxygen Species in Inflammation and Tissue Injury

Opioid receptor-triggered spinal mTORC1 activation contributes to morphine tolerance and hyperalgesia. - Abstract - Europe PMC

Counter-Regulation of Opioid Analgesia by Glial-Derived Bioactive Sphingolipids

JCI - Volume 117, Issue 11

Liproxstatin-1 Attenuates Morphine Tolerance through Inhibiting Spinal Ferroptosis-like Cell Death

Antioxidants, Free Full-Text

Isobolographic analysis of the opioid-opioid interactions in a tonic and a phasic mouse model of induced nociceptive pain, Journal of Biomedical Science

Involvement of NOX1/NADPH Oxidase in Morphine-Induced Analgesia and Tolerance

Liproxstatin-1 Attenuates Morphine Tolerance through Inhibiting Spinal Ferroptosis-like Cell Death